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Probiotics have a lower risk of drug and food interactions compared to traditional medications like vitamin K antagonists. However, they may still impact drug absorption and the composition of gut microbiota. In a previous review, Williams has examined the pharmacology, uses, dosage, safety, drug interactions, and contraindications of probiotics. It is important to note that probiotics can be found in foods and as supplements, and certain medications may interact with specific probiotic strains. There is a possibility that probiotic intake can alter drug absorption and metabolism, with potential implications for clinical use. There are FDA guidance documents for the use of probiotics as medical foods, and it has been reported that S. boulardii (a strain of probiotic) could interact with antifungal medications. This suggests that drugs may change the microbiota to favor certain taxa involved in metabolism.

Probiotics generally have a lower risk of drug and food interactions compared to traditional medications like vitamin K antagonists. However, they may still impact drug absorption and the composition of gut microbiota. Understanding the pharmacology, uses, dosage, safety, drug interactions, and contraindications of probiotics is important.

It's worth noting that probiotics can be found in foods and as supplements, and certain medications may interact with specific probiotic strains. The intake of probiotics can potentially alter drug absorption and metabolism, with implications for clinical use. For instance, there are FDA guidance documents for the use of probiotics as medical foods, and it has been reported that specific strains of probiotics, such as S. boulardii, could interact with antifungal medications.

In summary, while probiotics may have fewer interactions compared to traditional medications, there is still a need for caution and consideration, especially when they are concurrently used with other drugs or in specific patient populations.

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