where is pepsingine secreted to and from where

Pepsinogen is an inactive precursor (zymogen) of the enzyme pepsin, which plays a critical role in protein digestion. It is primarily secreted by specific cells known as chief cells, located in the gastric lining of the stomach.

Secretion Details:

  • Where is Pepsinogen Secreted From?
    Pepsinogen is secreted mainly by the chief cells found in the gastric mucosa (the lining of the stomach).

  • Where is Pepsinogen Secreted To?
    Once secreted, pepsinogen is released into the lumen of the gastric glands in the stomach.

Activation of Pepsinogen:

Pepsinogen is activated into its active form, pepsin, by the hydrochloric acid (HCl) secreted by the parietal cells in the stomach. This conversion is crucial for the enzyme to perform its function of breaking down proteins into smaller peptides.

For a more comprehensive understanding of pepsinogen, its secretion, and its role in digestion, you can refer to the following articles:

In summary, pepsinogen is secreted from the chief cells of the stomach into the gastric lumen, where it is activated by stomach acid to become pepsin, an essential enzyme for protein digestion.

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