The most common clinical presentation of sepsis includes infection and multiple organ failures, such as cardiovascular, renal, and respiratory. Signs of infection may include dysuria, smelly urine, and respiratory symptoms. Sepsis is a life-threatening condition caused by an uncontrolled response to infection, and in severe cases, septic shock can occur. Symptoms of sepsis may also include difficulty breathing, kidney failure, liver abnormalities, and changes in mental status. Diagnosis of sepsis can be challenging and there is no standard method for diagnosis. Studies have also shown a connection between delirium and mortality in patients with sepsis. Therefore, sepsis should be considered in patients with a suspected infection and worsening clinical condition.