Is Nitrate A Positive Or Negative Inotrope?

Possible summary:

Inotropes are medications that change the force of heart contractions, with nitrite showing strong negative inotropic effects. Nitroglycerin has a positive inotropic effect through increasing catecholamine release. These agents are often used in patients with systolic heart failure, but can also have adverse effects. Therapy combining vasodilators and inotropic agents is considered powerful in improving cardiac function.

Nitrate has a negative inotropic effect. Inotropes are medications that affect the force of heart contractions. Nitrate, specifically nitroglycerin, has a positive inotropic effect through increasing catecholamine release, but nitrate as a class exhibits a negative inotropic effect.

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