Increased Plasma Level Of Unconjugated Bilirubin And Stercobilinogen, Normal Serum

The text discusses the relationship between bilirubin and liver function. Elevated levels of unconjugated bilirubin can indicate prehepatic or hepatic jaundice, while an increase in conjugated bilirubin may suggest increased hemolysis or liver disease. Urobilinogen, a byproduct of bilirubin metabolism, can also indicate liver disease or damage when found in urine. Serum bilirubin levels are commonly used as a diagnostic marker for hepatic illnesses, as it reflects the liver's ability to process and secrete bilirubin. Neonatal jaundice, caused by high levels of unconjugated bilirubin in the blood, is a result of the breakdown of red blood cells. A high concentration of conjugated bilirubin in the plasma can indicate impaired liver function or hepatocellular disease.

The increased plasma level of unconjugated bilirubin and stercobilinogen, along with normal serum transaminase activity and the presence of urobilinogen, suggest a condition known as hemolytic jaundice. This typically occurs due to an increased breakdown of red blood cells, leading to elevated unconjugated bilirubin levels and the presence of stercobilinogen. Since serum transaminase activity is normal, liver function is not significantly affected, which is characteristic of hemolytic jaundice.

Measurement and clinical usefulness of bilirubin in liver diseaseJaypeeDigital | eBook Reader

Related Questions

Work fast from anywhere

Stay up to date and move work forward with BrutusAI on macOS/iOS/web & android. Download the app today.