Fasting, either through a fasting mimicking diet or through alternate day fasting, has been shown to reverse age-related changes in oligodendrocyte progenitor cells (OPCs) and improve their regenerative abilities. This, along with the use of the diabetes drug metformin, has been found to improve myelin repair in mice. Refeeding after an overnight fast also activates OPC differentiation and production in the brain. Additionally, research has shown that a 6-hour eating period and an 18-hour fasting period can switch the body's energy source to ketones, potentially benefiting those with multiple sclerosis (MS). These findings highlight the potential role of diet in promoting myelin repair and improving symptoms of neurological conditions such as MS.