The half-life of lithium carbonate varies among individuals and can range from approximately 18 to 36 hours. Some sources report it may be as short as 7 to 20 hours, while other studies suggest a median half-life of 24 to 28 hours, particularly in different physiological conditions such as age (with older adults experiencing longer half-lives).

In summary:

• Average half-life: 18 to 36 hours
• Typical estimates: 24 hours
• Variations can occur based on individual factors such as age and renal function.

For detailed pharmacokinetics and clinical considerations, you can refer to sources such as PubMed and Wikipedia's article on lithium (link: Wikipedia).

Sources

Lithium elimination half-life and duration of therapy - PubMedLithium carbonate: Uses, Interactions, Mechanism of Action[PDF] LITHOBID® (Lithium Carbonate USP) Extended-Release Tablets ...Lithium (medication) - WikipediaLithium Carbonate Tablets Prescription & Dosage Information - MPR24-Hour lithium concentration in human brain studied by Li-7 ...Lithium Toxicity: Practice Essentials, Background, Pathophysiology

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