Hume and Locke were both Empiricists, with a focus on epistemology. They believed in the reality of sense impressions and the importance of perception in acquiring knowledge. Hume argued that human actions are driven by passion rather than reason, while Locke believed that all knowledge is derived from sensory experiences. Both philosophers influenced the study of the human mind and its functions. However, Hume's belief in the constant flux of perceptions and Locke's view of personal identity as founded on consciousness stand out as major contributions.