This article reviews the current research on creatine supplementation and its potential effects on exercise performance and cognitive function. It explores the timing of creatine intake and compares the effectiveness of different types of creatine. Overall, the evidence suggests that creatine monohydrate supplementation is beneficial for exercise performance and may improve memory performance. However, more research is still needed on the impact of creatine timing and long-term supplementation on exercise training adaptations and clinical outcomes.