Yes, the use of lisinopril can lead to swollen lips as a side effect, specifically through a condition known as angioedema. Angioedema is characterized by swelling of the face, neck, and mouth, including the lips, and can result from the use of angiotensin-converting enzyme (ACE) inhibitors like lisinopril.

Several sources highlight that angioedema can manifest as swelling of the lips, tongue, or throat, which may become life-threatening if not addressed promptly. For instance, the Mayo Clinic advises patients to call their doctor immediately if they experience any swelling of the face or mouth while taking lisinopril. Here is more information from the Mayo Clinic.

Studies and professional reports indicate that although angioedema is not extremely common, it poses significant risks. It can occasionally lead to serious complications, including asphyxiation if airway involvement occurs. According to an article from Medsafe, the symptoms of ACE inhibitor-induced angioedema can include noticeable swelling of the lips, which necessitates urgent medical attention. For further details, you can refer to the Medsafe article here.

If you would like to read more about angioedema specifically related to ACE inhibitors or lisinopril, additional comprehensive information can be found here and in this detailed report by UpToDate.

In conclusion, if you or someone experiences swollen lips or other signs of angioedema while on lisinopril, it is crucial to seek medical attention immediately.

Sources

Lisinopril Swollen Lips - Consensus Academic Search EngineWhat Is ACE Inhibitor-Induced Angioedema, and How Do You Treat It?Lisinopril (oral route) - Mayo ClinicACE inhibitor-induced angioedema - UpToDateReminder: ACE inhibitor-induced angioedema can be fatal - MedsafeLisinopril and Angioedema: A Life-Threatening Side EffectWhat is Angioedema? - Poison Control

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