Amlodipine, a medication commonly used for treating hypertension and angina, has been associated with a variety of side effects, including skin rashes. The NHS notes that patients may experience rashes that can be swollen, raised, itchy, blistered, or peeling, which may indicate a serious allergic reaction to the drug. This information highlights the potential for skin reactions after extended use of amlodipine. You can read more about these side effects on the NHS website here.

According to Drugs.com, amlodipine can result in common side effects such as headaches, edema, and fatigue, with rashes being part of this list. This suggests that skin reactions can be a recognizable consequence of long-term amlodipine usage. Additional details regarding side effects can be found on their site here.

Moreover, a study published on Consultant360 emphasizes that eczematous drug eruptions induced by amlodipine should not be overlooked, especially in patients taking multiple medications. This further points to the importance of monitoring for skin reactions if amlodipine is used for an extended period. The study is available here.

Specific instances of skin reactions are documented in medical literature. For example, a case report detailed a patient who developed a petechial rash while on amlodipine therapy. This underscores that more serious dermatological conditions can arise due to the medication, which is discussed in a publication on PubMed here.

In summary, while skin rashes may not be the most common side effect associated with amlodipine, they are a recognized possibility, especially after long-term use. It’s crucial for patients on amlodipine to monitor for any unusual skin changes and consult with their healthcare provider for further evaluation and management.

Sources

Side effects of amlodipine - NHSAmlodipine Side Effects: Common, Severe, Long Term - Drugs.comAmlodipine-Induced Eczematous Drug Eruption - Consultant360Amlodipine-induced petechial rash - PubMedAmlodipine and atorvastatin (oral route) - Mayo ClinicRumpel-Leede Phenomenon in a Hypertensive Lady on AmlodipineAmlodipine-induced petechial rash - Bioline International

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