In summary, macrophages are highly versatile and multi-functional cells that play a crucial role in the body's immune system. They act as "cleaners" by removing dead and damaged cells and other waste materials. They also have a long lifespan and work together with neutrophils to respond to infections. Macrophages are easily obtainable and can be cultured and purified for research purposes. They also have a significant impact on the quality, duration, and intensity of inflammation. These cells are essential in organ development, host defense, acute and chronic inflammation, and tissue homeostasis and remodeling. Macrophages exist in two polarized forms and are beneficial in producing moderate levels of inflammation to aid in clearing infections.